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Treatment adherence in hemophilia

Prophylactic clotting-factor regimens reduce the occurrence of bleeding episodes and maintain joint health in individuals with moderate and severe hemophilia. However, these outcomes are only achieved with adherence to prescribed prophylaxis regimens. There are several types of barriers to adherence...

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Detalles Bibliográficos
Autores principales: Thornburg, Courtney D, Duncan, Natalie A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630068/
https://www.ncbi.nlm.nih.gov/pubmed/29033555
http://dx.doi.org/10.2147/PPA.S139851
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author Thornburg, Courtney D
Duncan, Natalie A
author_facet Thornburg, Courtney D
Duncan, Natalie A
author_sort Thornburg, Courtney D
collection PubMed
description Prophylactic clotting-factor regimens reduce the occurrence of bleeding episodes and maintain joint health in individuals with moderate and severe hemophilia. However, these outcomes are only achieved with adherence to prescribed prophylaxis regimens. There are several types of barriers to adherence related to key patient, condition, treatment, health-care system, and/or socioeconomic variables. Notably, health-care professionals may not prescribe prophylaxis if they perceive that a patient will be nonadherent. Prophylactic treatment strategies should be developed with the patient and family, focused on individualized treatment goals. Personalized strategies are needed to reinforce the importance of and encourage confidence in administering the regular infusions required for prophylactic therapy. These strategies may include verbal and written information delivered by health-care professionals, peers, and inter-active media. The advent of extended half-life clotting factors requiring less frequent infusion may improve adherence.
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spelling pubmed-56300682017-10-13 Treatment adherence in hemophilia Thornburg, Courtney D Duncan, Natalie A Patient Prefer Adherence Review Prophylactic clotting-factor regimens reduce the occurrence of bleeding episodes and maintain joint health in individuals with moderate and severe hemophilia. However, these outcomes are only achieved with adherence to prescribed prophylaxis regimens. There are several types of barriers to adherence related to key patient, condition, treatment, health-care system, and/or socioeconomic variables. Notably, health-care professionals may not prescribe prophylaxis if they perceive that a patient will be nonadherent. Prophylactic treatment strategies should be developed with the patient and family, focused on individualized treatment goals. Personalized strategies are needed to reinforce the importance of and encourage confidence in administering the regular infusions required for prophylactic therapy. These strategies may include verbal and written information delivered by health-care professionals, peers, and inter-active media. The advent of extended half-life clotting factors requiring less frequent infusion may improve adherence. Dove Medical Press 2017-09-27 /pmc/articles/PMC5630068/ /pubmed/29033555 http://dx.doi.org/10.2147/PPA.S139851 Text en © 2017 Thornburg and Duncan. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Thornburg, Courtney D
Duncan, Natalie A
Treatment adherence in hemophilia
title Treatment adherence in hemophilia
title_full Treatment adherence in hemophilia
title_fullStr Treatment adherence in hemophilia
title_full_unstemmed Treatment adherence in hemophilia
title_short Treatment adherence in hemophilia
title_sort treatment adherence in hemophilia
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630068/
https://www.ncbi.nlm.nih.gov/pubmed/29033555
http://dx.doi.org/10.2147/PPA.S139851
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