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Activation of cannabinoid receptor type II by AM1241 protects adipose-derived mesenchymal stem cells from oxidative damage and enhances their therapeutic efficacy in myocardial infarction mice via Stat3 activation

The poor survival of cells in ischemic sites diminishes the therapeutic efficacy of stem cell therapy. Previously we and others have reported that Cannabinoid receptor type II (CB2) is protective during heart ischemic injury for its anti-oxidative activity. However, whether CB2 activation could impr...

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Detalles Bibliográficos
Autores principales: Han, Dong, Li, Xiang, Fan, Wen-Si, Chen, Jiang-Wei, Gou, Tian-Tian, Su, Tao, Fan, Miao-Miao, Xu, Meng-Qi, Wang, Ya-Bin, Ma, Sai, Qiu, Ya, Cao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630296/
https://www.ncbi.nlm.nih.gov/pubmed/29029396
http://dx.doi.org/10.18632/oncotarget.17614