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Activation of cannabinoid receptor type II by AM1241 protects adipose-derived mesenchymal stem cells from oxidative damage and enhances their therapeutic efficacy in myocardial infarction mice via Stat3 activation
The poor survival of cells in ischemic sites diminishes the therapeutic efficacy of stem cell therapy. Previously we and others have reported that Cannabinoid receptor type II (CB2) is protective during heart ischemic injury for its anti-oxidative activity. However, whether CB2 activation could impr...
Autores principales: | Han, Dong, Li, Xiang, Fan, Wen-Si, Chen, Jiang-Wei, Gou, Tian-Tian, Su, Tao, Fan, Miao-Miao, Xu, Meng-Qi, Wang, Ya-Bin, Ma, Sai, Qiu, Ya, Cao, Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630296/ https://www.ncbi.nlm.nih.gov/pubmed/29029396 http://dx.doi.org/10.18632/oncotarget.17614 |
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