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Rat embryonic fibroblasts immortalized by MRPS18-2 protein are target for NK-cells

Overexpression of the human mitochondrial ribosomal protein MRPS18-2 (S18-2) led to immortalization of primary rat embryonic fibroblasts (REFs). The derived cells (18IM) expressed embryonic stem cell markers. Noteworthy, genes encoding the COX family proteins were up-regulated significantly. It is k...

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Detalles Bibliográficos
Autores principales: Mushtaq, Muhammad, Pangigadde, Pradeepa N., Darekar, Suhas, Dissen, Erik, Kashuba, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630300/
https://www.ncbi.nlm.nih.gov/pubmed/29029400
http://dx.doi.org/10.18632/oncotarget.17610