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The value of phosphohistone H3 as a proliferation marker for evaluating invasive breast cancers: A comparative study with Ki67

BACKGROUND: Established measurements of proliferation in breast cancer are Ki67 and mitotic-activity-index (MAI), with problems in reproducibility and prognostic accuracy. Phosphohistone H3 (PHH3), a relatively novel IHC marker is specific for mitosis with good reproducibility. We hypothesized that...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Ye, Jeong, Hyang Sook, Chung, Taek, Kim, Moonsik, Lee, Ji Hee, Jung, Woo Hee, Koo, Ja Seung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630312/
https://www.ncbi.nlm.nih.gov/pubmed/29029412
http://dx.doi.org/10.18632/oncotarget.17775

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