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Generation and evaluation of antibody agents for molecular imaging of CD44v6-expressing cancers
AIM: The aim of this study was to generate and characterize scFv antibodies directed to human CD44v6, as well as to radiolabel and evaluate top candidates in vitro and in vivo for their potential use in CD44v6-targeted molecular imaging in cancer patients. MATERIALS AND METHODS: Phage display select...
Autores principales: | Haylock, Anna-Karin, Nilvebrant, Johan, Mortensen, Anja, Velikyan, Irina, Nestor, Marika, Falk, Ronny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630320/ https://www.ncbi.nlm.nih.gov/pubmed/29029420 http://dx.doi.org/10.18632/oncotarget.17996 |
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