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The involvement of Nrf2 in the protective effects of (-)-Epigallocatechin-3-gallate (EGCG) on NaAsO(2)-induced hepatotoxicity

Arsenic exposure produces hepatotoxicity. The common mechanism determining its toxicity is the generation of oxidative stress. Oxidative stress induced by arsenic leads to the activation of nuclear factor erythroid 2-related factor 2 (Nrf2) pathway. (-)-Epigallocatechin-3-gallate (EGCG) possesses a...

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Detalles Bibliográficos
Autores principales: Han, Xiao-Dong, Zhang, Yan-Yan, Wang, Ke-Lei, Huang, Yong-Pan, Yang, Zhong-Bao, Liu, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630332/
https://www.ncbi.nlm.nih.gov/pubmed/29029432
http://dx.doi.org/10.18632/oncotarget.18582

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