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H(2)O(2) attenuates IGF-1R tyrosine phosphorylation and its survival signaling properties in neuronal cells via NR2B containing NMDA receptor

Impairment of insulin-like growth factor I (IGF-I) signaling plays an important role in the development of neurodegeneration. In the present study, we investigated the effect of H(2)O(2) on the survival signaling of IGF-1 and its underlying mechanisms in human neuronal cells SH-SY5Y. Our results sho...

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Detalles Bibliográficos
Autores principales:	Zeng, Zhiwen, Wang, Dejun, Gaur, Uma, Rifang, Liao, Wang, Haitao, Zheng, Wenhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630333/ https://www.ncbi.nlm.nih.gov/pubmed/29029433 http://dx.doi.org/10.18632/oncotarget.18625

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