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Silencing protein kinase C ζ by microRNA-25-5p activates AMPK signaling and inhibits colorectal cancer cell proliferation

Developing novel strategies against human colorectal cancer (CRC) cells is needed. Activation of AMP-activated protein kinase (AMPK) could possibly inhibit CRC cells. Protein kinase C ζ (PKCζ) is an AMPK negative regulator. Here we found that PKCζ expression was significantly elevated in human colon...

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Detalles Bibliográficos
Autores principales:	Zhang, Shihu, Zhang, Yiyang, Cheng, Qing, Ma, Zhaoqun, Gong, Guanwen, Deng, Zhengming, Xu, Kun, Wang, Gaoyuan, Wei, Yousong, Zou, Xiaoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630334/ https://www.ncbi.nlm.nih.gov/pubmed/29029434 http://dx.doi.org/10.18632/oncotarget.18649

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