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A potential prognostic biomarker SPC24 promotes tumorigenesis and metastasis in lung cancer
RESULTS: SPC24 is over-expressed in clinical lung adenocarcinoma samples, and high level of SPC24 is associated with advanced stages of lung tumors. Knocking down SPC24 repressed cell growth and promoted apoptosis. SPC24 deficiency reduced cancer cell migration as well. E-cadherin, one of the epithe...
Autores principales: | Zhou, Juan, Yu, Yang, Pei, Yunfeng, Cao, Chunping, Ding, Chen, Wang, Duping, Sun, Li, Niu, Guoping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630346/ https://www.ncbi.nlm.nih.gov/pubmed/29029446 http://dx.doi.org/10.18632/oncotarget.18971 |
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