PTEN loss detection in prostate cancer: comparison of PTEN immunohistochemistry and PTEN FISH in a large retrospective prostatectomy cohort

PTEN deletion is an established prognostic biomarker in prostate cancer. We compared PTEN immunohistochemistry (IHC) and PTEN fluorescence in situ hybridization (FISH) in the largest existing radical prostatectomy cohort with clinical follow-up data. There was high concordance between IHC and FISH:...

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Detalles Bibliográficos
Autores principales: Lotan, Tamara L., Heumann, Asmus, Rico, Sebastian Dwertmann, Hicks, Jessica, Lecksell, Kristen, Koop, Christina, Sauter, Guido, Schlomm, Thorsten, Simon, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630353/
https://www.ncbi.nlm.nih.gov/pubmed/29029453
http://dx.doi.org/10.18632/oncotarget.19217

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