Cargando…
GATA2 regulates the erythropoietin receptor in t(12;21) ALL
The t(12;21) (p13;q22) chromosomal translocation resulting in the ETV6/RUNX1 fusion gene is the most frequent structural cytogenetic abnormality in children with acute lymphoblastic leukemia (ALL). The erythropoietin receptor (EPOR), usually associated with erythroid progenitor cells, is highly expr...
Autores principales: | Gaine, Marie E., Sharpe, Daniel J., Smith, James S., Colyer, Hilary A.A., Hodges, Vivien M., Lappin, Terry R., Mills, Ken I. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630392/ https://www.ncbi.nlm.nih.gov/pubmed/29029492 http://dx.doi.org/10.18632/oncotarget.19792 |
Ejemplares similares
-
Extra Copies of der(21)t(12;21) plus Deletion of ETV6 Gene due to dic(12;18) in B-Cell Precursor ALL with Poor Outcome
por: Hernandes, Marina Araújo Fonzar, et al.
Publicado: (2012) -
Fluorescence in situ Hybridization Analysis of 12;21 Translocation in Japanese Childhood Acute Lymphoblastic Leukemia
por: Eguchi‐Ishimae, Minenori, et al.
Publicado: (1998) -
ARHGEF4 Regulates an Essential Oncogenic Program in t(12;21)-Associated Acute Lymphoblastic Leukemia
por: Virely, Clemence, et al.
Publicado: (2020) -
The Landscape of Secondary Genetic Rearrangements in Pediatric Patients with B-Cell Acute Lymphoblastic Leukemia with t(12;21)
por: Kaczmarska, Agnieszka, et al.
Publicado: (2023) -
Erythropoietin in bone homeostasis—Implications for efficacious anemia therapy
por: Lappin, Katrina M., et al.
Publicado: (2021)