KRAS overexpression independent of RAS mutations confers an adverse prognosis in cytogenetically normal acute myeloid leukemia

The prognostic value of RAS mutations has been systematically investigated in acute myeloid leukemia (AML). However, clinical significance of RAS expressions in AML remains poorly determined. To explore the clinical significance, we analyzed KRAS and NRAS expressions in 143 de novo AML patients by r...

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Detalles Bibliográficos
Autores principales: Zhou, Jing-Dong, Yao, Dong-Ming, Li, Xi-Xi, Zhang, Ting-Juan, Zhang, Wei, Ma, Ji-Chun, Guo, Hong, Deng, Zhao-Qun, Lin, Jiang, Qian, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630394/
https://www.ncbi.nlm.nih.gov/pubmed/29029494
http://dx.doi.org/10.18632/oncotarget.19798

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