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Generation and characterization of ErbB2-CAR-engineered cytokine-induced killer cells for the treatment of high-risk soft tissue sarcoma in children

Pediatric patients with recurrent, refractory or advanced soft tissue sarcoma (STS) who are simultaneously showing signs of cumulative treatment toxicity are in need of novel therapies. In this preclinical analysis, we identified ErbB2 as a targetable antigen on STS cells and used cytokine-induced k...

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Detalles Bibliográficos
Autores principales:	Merker, Michael, Pfirrmann, Verena, Oelsner, Sarah, Fulda, Simone, Klingebiel, Thomas, Wels, Winfried S., Bader, Peter, Rettinger, Eva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630399/ https://www.ncbi.nlm.nih.gov/pubmed/29029499 http://dx.doi.org/10.18632/oncotarget.19821

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