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Meta-analysis of the clinical characteristics and prognostic relevance of NOTCH1 and FBXW7 mutation in T-cell acute lymphoblastic leukemia

The NOTCH1 signaling pathway is crucial for T-cell development, and NOTCH1 and/or FBXW7 mutations are frequently detected in T-cell acute lymphoblastic leukemia (T-ALL). We performed a systematic review and meta-analysis of 18 randomized controlled trials (RCTs) to assess the prognostic impact of mu...

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Detalles Bibliográficos
Autores principales: Liu, Rong-Bin, Guo, Jian-Gui, Liu, Tian-Ze, Guo, Cheng-Cheng, Fan, Xin-Xiang, Zhang, Xiao, Hu, Wei-Han, Cai, Xiu-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630418/
https://www.ncbi.nlm.nih.gov/pubmed/29029518
http://dx.doi.org/10.18632/oncotarget.18576