Biotin tagging of MeCP2 in mice reveals contextual insights into the Rett syndrome transcriptome

Mutations in MECP2 cause Rett syndrome (RTT), an X-linked neurological disorder characterized by regressive loss of neurodevelopmental milestones and acquired psychomotor deficits. However, the cellular heterogeneity of the brain impedes an understanding of how MECP2 mutations contribute to RTT. Her...

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Detalles Bibliográficos
Autores principales: Johnson, B.S., Zhao, Y.T., Fasolino, M., Lamonica, J.M., Kim, Y.J., Georgakilas, G., Wood, K.H., Bu, D., Cui, Y., Goffin, D., Vahedi, G., Kim, T.H., Zhou, Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630512/
https://www.ncbi.nlm.nih.gov/pubmed/28920956
http://dx.doi.org/10.1038/nm.4406

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