Enhancing excitatory activity of somatosensory cortex alleviates neuropathic pain through regulating homeostatic plasticity

Central sensitization and network hyperexcitability of the nociceptive system is a basic mechanism of neuropathic pain. We hypothesize that development of cortical hyperexcitability underlying neuropathic pain may involve homeostatic plasticity in response to lesion-induced somatosensory deprivation...

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Detalles Bibliográficos
Autores principales: Xiong, Wenhui, Ping, Xingjie, Ripsch, Matthew S., Chavez, Grace Santa Cruz, Hannon, Heidi Elise, Jiang, Kewen, Bao, Chunhui, Jadhav, Vaishnavi, Chen, Lifang, Chai, Zhi, Ma, Cungen, Wu, Huangan, Feng, Jianqiao, Blesch, Armin, White, Fletcher A., Jin, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630599/
https://www.ncbi.nlm.nih.gov/pubmed/28986567
http://dx.doi.org/10.1038/s41598-017-12972-6

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