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Unraveling Drug Penetration of Echinocandin Antifungals at the Site of Infection in an Intra-Abdominal Abscess Model
BACKGROUND: Intra-abdominal candidiasis (IAC) is a prominent invasive fungal infection associated with high mortality. Prompt antifungal therapy and source control are crucial for successful treatment. Echinocandin antifungal drugs are first-line agents. Yet, their clinical effectiveness is highly v...
Autores principales: | Zhao, Yanan, Prideaux, Brendan, Nagasaki, Yoji, Lee, Min Hee, Chen, Pei-Yu, Blanc, Landry, Ho, Hsinpin, Clancy, Cornelius J, Nguyen, Minh-Hong, Dartois, Veronique, Perlin, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630820/ http://dx.doi.org/10.1093/ofid/ofx163.1229 |
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