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Activity of Ceftolozane-Tazobactam (C/T) against Escherichia coli Isolates from U.S. Veterans in Relation to Co-resistance and Sequence Type 131 (ST131) H30/H30Rx Status

BACKGROUND: E. coli ST131, with its resistance-associated H30 and H30Rx clonal subsets, causes most antimicrobial-resistant E. coli infections, especially among veterans. The activity of the novel combination agent C/T against ST131 is undefined. METHODS: E. coli clinical isolates (n = 595), includi...

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Detalles Bibliográficos
Autores principales: Johnston, Brian D, Thuras, Paul, Johnson, James R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630858/
http://dx.doi.org/10.1093/ofid/ofx163.921