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In vivo Pharmacodynamic Evaluation of Omadacycline (PTK 0796) against Staphylococcus aureus (SA) in the Murine Thigh Infection Model

BACKGROUND: Omadacycline is a novel aminomethylcycline antibiotic in development for acute bacterial skin and skin structure infection (ABSSSI) and community acquired bacterial pneumonia (CABP). The goal of the study was to determine the PK/PD targets in the murine thigh infection model against a di...

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Detalles Bibliográficos
Autores principales:	Lepak, Alexander J, Zhao, Miao, Marchillo, Karen, VanHecker, Jamie, Andes, David R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630942/ http://dx.doi.org/10.1093/ofid/ofx163.1227

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