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Paralog-Specific Patterns of Structural Disorder and Phosphorylation in the Vertebrate SH3–SH2–Tyrosine Kinase Protein Family

One of the largest multigene families in Metazoa are the tyrosine kinases (TKs). These are important multifunctional proteins that have evolved as dynamic switches that perform tyrosine phosphorylation and other noncatalytic activities regulated by various allosteric mechanisms. TKs interact with ea...

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Detalles Bibliográficos
Autores principales: Dos Santos, Helena G., Siltberg-Liberles, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630953/
https://www.ncbi.nlm.nih.gov/pubmed/27519537
http://dx.doi.org/10.1093/gbe/evw194

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