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Fungal Cytological Profiling of Candida albicans Exposed to Diverse Antifungal Agents Including the Novel Gwt1 inhibitor APX001A

BACKGROUND: Bacterial cytological profiling accelerates drug discovery efforts by determining the mechanism of action (MOA) of newly developed antibacterial agents. Our goal was to adapt this technology to the identification and study of the MOA of antifungal compounds. Here we explore the utility o...

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Detalles Bibliográficos
Autores principales: Sharp, Marc, Soltow, Quinlyn, Shaw, Karen Joy, Pogliano, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631029/
http://dx.doi.org/10.1093/ofid/ofx163.1218

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