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SCY-078 Demonstrates Significant Tissue Penetration in Rats and Mice Following Oral or IV Administration
BACKGROUND: The ability of a pharmacologic agent to reach target organ(s) in therapeutically-meaningful concentrations is one of the fundamental considerations when developing effective, anti-infective treatments. SCY-078 is a novel, oral and intravenous (IV), triterpenoid glucan synthase inhibitor...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631121/ http://dx.doi.org/10.1093/ofid/ofx163.1204 |