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Efficacy Evaluation of Iclaprim in a Neutropenic Rat Lung Infection Model with Methicillin-Resistant Staphylococcus aureus Entrapped in Alginate Microspheres

BACKGROUND: The objective of this study was to demonstrate the effect of iclaprim, a new generation diaminopyrimidine, in a neutropenic rat lung infection model with methicillin resistant Staphylococcus aureus (MRSA). METHODS: S. aureus strain AH1252, a thymidine knockout of the MRSA wild type AW6 s...

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Detalles Bibliográficos
Autores principales:	Huang, David, Hawser, Stephen, Morrissey, Ian, Murphy, Timothy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631203/ http://dx.doi.org/10.1093/ofid/ofx163.1221

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