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DS11960558, A Water Soluble Prodrug of DS-2969b, for Intravenous Treatment of Clostridium difficile Infection
BACKGROUND: Clostridium difficile infection (CDI) is the most common cause of diarrhea in hospitals. The only available intravenous (IV) therapy for CDI is metronidazole, which showed only a 52.4% cure rate in a prospective observational study. DS11960558 is a water-soluble prodrug of DS-2969b, whic...
Autores principales: | Yamada, Makiko, Uchiyama, Minoru, Inoue, Shin-Ichi, Deguchi, Tsuneo, Furuta, Yoshitake, Yabe, Koichi, Masuda, Nobuhisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631360/ http://dx.doi.org/10.1093/ofid/ofx163.1212 |
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