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Enhanced Potency and Durability of Antibody Response to Seasonal Trivalent Inactivated Influenza Vaccine (TIV) Combined with a Novel Water-in-Oil Adjuvant System at Reduced Hemagglutinin (HA) Doses
BACKGROUND: New influenza vaccines are needed to increase vaccine efficacy against infection and illness. Adjuvants may allow HA dose-sparing while increasing the antibody response. MAS-1 is an investigational low viscosity, free-flowing, water-in-oil emulsion-based adjuvant delivery system with sta...
Autores principales: | Gorse, Geoffrey J, Grimes, Stephen, Buck, Helen, Mulla, Hussain, White, Peter, Graham, Irene, Treanor, John J, Hill, Heather, May, Jeanine, Blackburn, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631365/ http://dx.doi.org/10.1093/ofid/ofx163.1159 |
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