Aberrant Autophagy in Macrophages and Astrocytes after HIV Nef or Antiretroviral Treatment: Contribution to the Pathogenesis of HIV-associated Neurocognitive Disorders

BACKGROUND: Despite antiretroviral therapy (ART), HIV-associated neurocognitive disorders (HAND) still affect 40–70% of HIV-infected people. The pathogenesis of HAND is multi-factorial and poorly understood. Macroautophagy is a cellular self-digestion process with essential roles in defense against...

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Detalles Bibliográficos
Autores principales: Cheney, Laura, Calderon, Tina, Cuervo, Ana Maria, Berman, Joan W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631599/
http://dx.doi.org/10.1093/ofid/ofx163.407

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