Serum and Lung Pharmacokinetics of ASN100, a Monoclonal Antibody Combination for the Prevention and Treatment of Staphylococcus aureus Pneumonia

BACKGROUND: Monoclonal antibodies (mAbs) are well-suited for the prevention and treatment of acute bacterial infections. ASN100 is a combination of two fully human IgG1 mAbs, ASN-1 and ASN-2 that together neutralize six Staphylococcus aureus cytotoxins, alpha-hemolysin (Hla) and five leukocidins (Hl...

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Detalles Bibliográficos
Autores principales: Magyarics, Zoltan, Leslie, Fraser, Luperchio, Steven A, Bartko, Johann, Schörgenhofer, Christian, Schwameis, Michael, Derhaschnig, Ulla, Lagler, Heimo, Stiebellehner, Leopold, Jilma, Bernd, Stevens, Christopher, Nagy, Eszter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631769/
http://dx.doi.org/10.1093/ofid/ofx163.722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631769/
http://dx.doi.org/10.1093/ofid/ofx163.722

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