De novo STAT3 Mutation in a Patient with Fatal, Treatment-Refractory Sino-orbital Aspergillosis

BACKGROUND: Signal transducer and activator of transcription 3 (STAT3) loss-of-function mutations in humans result in Job’s syndrome, characterized by elevated IgE, bacterial infections, chronic mucocutaneous candidiasis, pulmonary aspergillosis due to structural lung disease, and connective tissue...

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Detalles Bibliográficos
Autores principales: Natarajan, Mukil, Hsu, Amy, Weinreich, Michael, Sugui, Janyce, Zangeneh, Tirdad, Carr, Tara, Oler, Andrew, Similuk, Morgan, Kwon-Chung, Kyung, Milner, Joshua, Lionakis, Michail S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
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Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631805/
http://dx.doi.org/10.1093/ofid/ofx163.130

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