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SYN-004 (ribaxamase) prevents New Onset Clostridium difficile Infection by Protecting the Integrity Gut Microbiome in a Phase 2b Study

BACKGROUND: Clostridium difficile infections (CDI) are an “urgent threat,” but there are no approved drugs or vaccines to prevent new onset CDI. SYN-004 (ribaxamase) is a β-lactamase designed to be orally administered with IV β-lactam antibiotics and remain localized in the intestine to degrade anti...

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Detalles Bibliográficos
Autores principales:	Kokai-Kun, John, Roberts, Tracey, Coughlin, Olivia, Whalen, Heidi, Le, Charles, Da Costa, Christopher, Sliman, Joseph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631845/ http://dx.doi.org/10.1093/ofid/ofx162.029

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