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Complicated Staphylococcus aureus Bacteremia (SAB) Is Associated with Genetic Variation in GLS2

BACKGROUND: SAB is a serious, common infection. We used whole exome sequencing (WES) to examine the cumulative effect of coding variants in each gene on risk of complicated SAB in a discovery set of patients, and then evaluated the nominally significant genes in a replication set of patients using c...

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Detalles Bibliográficos
Autores principales: Fowler, Vance, Ruffin, Felicia, Kuinkel, Batu Sharma, Cyr, Derek D, Guo, Shengru, Dykxhoorn, Derek, Skov, Robert, Bruun, Niels, Dahl, Anders, Lærke, Christian, Scott, William, Andersen, Paal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632279/
http://dx.doi.org/10.1093/ofid/ofx162.110