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Organic anion transporters, OAT1 and OAT3, are crucial biopterin transporters involved in bodily distribution of tetrahydrobiopterin and exclusion of its excess

Tetrahydrobiopterin (BH(4)) is a common coenzyme of phenylalanine-, tyrosine-, and tryptophan hydroxylases, alkylglycerol monooxygenase, and NO synthases (NOS). Synthetic BH(4) is used medicinally for BH(4)-responsive phenylketonuria and inherited BH(4) deficiency. BH(4) supplementation has also dra...

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Detalles Bibliográficos
Autores principales:	Ohashi, Akiko, Mamada, Kaori, Harada, Tomonori, Naito, Masako, Takahashi, Tomihisa, Aizawa, Shin, Hasegawa, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632347/ https://www.ncbi.nlm.nih.gov/pubmed/28534121 http://dx.doi.org/10.1007/s11010-017-3060-7

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