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Estimating and Interpreting Effects from Nonlinear Exposure-Response Curves in Occupational Cohorts Using Truncated Power Basis Expansions and Penalized Splines

Truncated power basis expansions and penalized spline methods are demonstrated for estimating nonlinear exposure-response relationships in the Cox proportional hazards model. R code is provided for fitting models to get point and interval estimates. The method is illustrated using a simulated data s...

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Detalles Bibliográficos
Autores principales: Malloy, Elizabeth J., Kapellusch, Jay M., Garg, Arun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632483/
https://www.ncbi.nlm.nih.gov/pubmed/29312462
http://dx.doi.org/10.1155/2017/7518035

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