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Cobalt-catalysed reductive C–H alkylation of indoles using carboxylic acids and molecular hydrogen
The direct CH-alkylation of indoles using carboxylic acids is presented for the first time. The catalytic system based on the combination of Co(acac)(3) and 1,1,1-tris(diphenylphosphinomethyl)-ethane (Triphos, L1), in the presence of Al(OTf)(3) as co-catalyst, is able to perform the reductive alkyla...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632795/ https://www.ncbi.nlm.nih.gov/pubmed/29163930 http://dx.doi.org/10.1039/c7sc02117h |