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Cytotoxic (salen)ruthenium(iii) anticancer complexes exhibit different modes of cell death directed by axial ligands

Two novel series of (salen)ruthenium(iii) complexes bearing guanidine and amidine axial ligands were synthesized, characterized, and evaluated for anticancer activity. In vitro cytotoxicity tests demonstrate that these complexes are cytotoxic against various cancer cell lines and the leading complex...

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Detalles Bibliográficos
Autores principales: Li, Cai, Ip, Kwok-Wa, Man, Wai-Lun, Song, Dan, He, Ming-Liang, Yiu, Shek-Man, Lau, Tai-Chu, Zhu, Guangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632802/
https://www.ncbi.nlm.nih.gov/pubmed/29147511
http://dx.doi.org/10.1039/c7sc02205k