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Paroxysmal Nocturnal Hemoglobinuria in Pregnancy: A Dilemma in Treatment and Thromboprophylaxis

Paroxysmal nocturnal hemoglobinuria (PNH) is a hematologic disorder characterized by an acquired somatic mutation in the phosphatidylinositol glycan class A gene which leads to a higher risk for increased venous and arterial thrombosis. Current treatment for PNH includes eculizumab. Pregnant patient...

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Detalles Bibliográficos
Autores principales: Patel, Arpan, Unnikrishnan, Athira, Murphy, Martina, Egerman, Robert, Wheeler, Sarah, Richards, Ashley, Wingard, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632866/
https://www.ncbi.nlm.nih.gov/pubmed/29147590
http://dx.doi.org/10.1155/2017/7289126