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Tumor-induced osteomalacia

Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome clinically characterized by bone pain, fractures and muscle weakness. It is caused by tumoral overproduction of fibroblast growth factor 23 (FGF23) that acts primarily at the proximal renal tubule, decreasing phosphate reabsorption a...

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Detalles Bibliográficos
Autores principales: Florenzano, Pablo, Gafni, Rachel I., Collins, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633085/
https://www.ncbi.nlm.nih.gov/pubmed/29021995
http://dx.doi.org/10.1016/j.bonr.2017.09.002