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A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds
The present review is a sequel to the previous review on cancer metabolism published in this journal. This review focuses on the selective antiproliferative and cytotoxic effects of mitochondria-targeted therapeutics (MTTs) in cancer cells. Emerging research reveals a key role of mitochondrial respi...
Autores principales: | Kalyanaraman, Balaraman, Cheng, Gang, Hardy, Micael, Ouari, Olivier, Lopez, Marcos, Joseph, Joy, Zielonka, Jacek, Dwinell, Michael B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633086/ https://www.ncbi.nlm.nih.gov/pubmed/29017115 http://dx.doi.org/10.1016/j.redox.2017.09.020 |
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