Data on the effect of knockout of cytohesin-1 in myelination-related protein kinase signaling

Cytohesin-1 is the guanine-nucleotide exchange factor of Arf6, a small GTPase of Arf family, and participates in cellular morphological changes. Knockout mice of cytohesin-1 exhibit decreased myelination of neuronal axons in the peripheral nervous system (PNS) “Phosphorylation of cytohesin-1 by Fyn...

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Autores principales: Tsuneishi, Ruri, Matsumoto, Naoto, Itaoka, Misa, Urai, Yuri, Kaneko, Minami, Watanabe, Natsumi, Takashima, Shou, Seki, Yoichi, Morimoto, Takako, Sakagami, Hiroyuki, Miyamoto, Yuki, Yamauchi, Junji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Agricultural and Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633161/
https://www.ncbi.nlm.nih.gov/pubmed/29022003
http://dx.doi.org/10.1016/j.dib.2017.09.024
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author Tsuneishi, Ruri
Matsumoto, Naoto
Itaoka, Misa
Urai, Yuri
Kaneko, Minami
Watanabe, Natsumi
Takashima, Shou
Seki, Yoichi
Morimoto, Takako
Sakagami, Hiroyuki
Miyamoto, Yuki
Yamauchi, Junji
author_facet Tsuneishi, Ruri
Matsumoto, Naoto
Itaoka, Misa
Urai, Yuri
Kaneko, Minami
Watanabe, Natsumi
Takashima, Shou
Seki, Yoichi
Morimoto, Takako
Sakagami, Hiroyuki
Miyamoto, Yuki
Yamauchi, Junji
author_sort Tsuneishi, Ruri
collection PubMed
description Cytohesin-1 is the guanine-nucleotide exchange factor of Arf6, a small GTPase of Arf family, and participates in cellular morphological changes. Knockout mice of cytohesin-1 exhibit decreased myelination of neuronal axons in the peripheral nervous system (PNS) “Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development (Yamauchi et al., 2012) [1]”. Herein we provide the data regarding decreased phosphorylation levels of protein kinases involved in two major myelination-related kinase cascades in cytohesin-1 knockout mice.
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spelling pubmed-56331612017-10-11 Data on the effect of knockout of cytohesin-1 in myelination-related protein kinase signaling Tsuneishi, Ruri Matsumoto, Naoto Itaoka, Misa Urai, Yuri Kaneko, Minami Watanabe, Natsumi Takashima, Shou Seki, Yoichi Morimoto, Takako Sakagami, Hiroyuki Miyamoto, Yuki Yamauchi, Junji Data Brief Agricultural and Biological Sciences Cytohesin-1 is the guanine-nucleotide exchange factor of Arf6, a small GTPase of Arf family, and participates in cellular morphological changes. Knockout mice of cytohesin-1 exhibit decreased myelination of neuronal axons in the peripheral nervous system (PNS) “Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development (Yamauchi et al., 2012) [1]”. Herein we provide the data regarding decreased phosphorylation levels of protein kinases involved in two major myelination-related kinase cascades in cytohesin-1 knockout mice. Elsevier 2017-09-20 /pmc/articles/PMC5633161/ /pubmed/29022003 http://dx.doi.org/10.1016/j.dib.2017.09.024 Text en © 2017 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Agricultural and Biological Sciences
Tsuneishi, Ruri
Matsumoto, Naoto
Itaoka, Misa
Urai, Yuri
Kaneko, Minami
Watanabe, Natsumi
Takashima, Shou
Seki, Yoichi
Morimoto, Takako
Sakagami, Hiroyuki
Miyamoto, Yuki
Yamauchi, Junji
Data on the effect of knockout of cytohesin-1 in myelination-related protein kinase signaling
title Data on the effect of knockout of cytohesin-1 in myelination-related protein kinase signaling
title_full Data on the effect of knockout of cytohesin-1 in myelination-related protein kinase signaling
title_fullStr Data on the effect of knockout of cytohesin-1 in myelination-related protein kinase signaling
title_full_unstemmed Data on the effect of knockout of cytohesin-1 in myelination-related protein kinase signaling
title_short Data on the effect of knockout of cytohesin-1 in myelination-related protein kinase signaling
title_sort data on the effect of knockout of cytohesin-1 in myelination-related protein kinase signaling
topic Agricultural and Biological Sciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633161/
https://www.ncbi.nlm.nih.gov/pubmed/29022003
http://dx.doi.org/10.1016/j.dib.2017.09.024
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