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Inhibition of melanization by serpin-5 and serpin-9 promotes baculovirus infection in cotton bollworm Helicoverpa armigera

Melanization, an important insect defense mechanism, is mediated by clip-domain serine protease (cSP) cascades and is regulated by serpins. Here we show that proteolytic activation of prophenoloxidase (PPO) and PO-catalyzed melanization kill the baculovirus in vitro. Our quantitative proteomics and...

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Detalles Bibliográficos
Autores principales:	Yuan, Chuanfei, Xing, Longsheng, Wang, Manli, Wang, Xi, Yin, Mengyi, Wang, Qianran, Hu, Zhihong, Zou, Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633200/ https://www.ncbi.nlm.nih.gov/pubmed/28953952 http://dx.doi.org/10.1371/journal.ppat.1006645

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