In Vivo Production of Monoclonal Antibodies by Gene Transfer via Electroporation Protects against Lethal Influenza and Ebola Infections

Monoclonal antibodies (mAbs) have wide clinical utility, but global access is limited by high costs and impracticalities associated with repeated passive administration. Here, we describe an optimized electroporation-based DNA gene transfer platform technology that can be utilized for production of...

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Detalles Bibliográficos
Autores principales: Andrews, Chasity D., Luo, Yang, Sun, Ming, Yu, Jian, Goff, Arthur J., Glass, Pamela J., Padte, Neal N., Huang, Yaoxing, Ho, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633264/
https://www.ncbi.nlm.nih.gov/pubmed/29034261
http://dx.doi.org/10.1016/j.omtm.2017.09.003

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