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Whole Genome Sequencing-Based Mapping and Candidate Identification of Mutations from Fixed Zebrafish Tissue

As forward genetic screens in zebrafish become more common, the number of mutants that cannot be identified by gross morphology or through transgenic approaches, such as many nervous system defects, has also increased. Screening for these difficult-to-visualize phenotypes demands techniques such as...

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Detalles Bibliográficos
Autores principales: Sanchez, Nicholas E., Harty, Breanne L., O’Reilly-Pol, Thomas, Ackerman, Sarah D., Herbert, Amy L., Holmgren, Melanie, Johnson, Stephen L., Gray, Ryan S., Monk, Kelly R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633390/
https://www.ncbi.nlm.nih.gov/pubmed/28855284
http://dx.doi.org/10.1534/g3.117.300212