Revealing the genomic differences between two subgroups in Lactobacillus gasseri

Being an autochthonous species in humans, Lactobacillus gasseri is widely used as a probiotic for fermented products. We thoroughly compared the gene contents of 75 L. gasseri genomes and identified two intraspecific groups by the average nucleotide identity (ANI) threshold of 94%. Group I, with 48...

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Detalles Bibliográficos
Autores principales: TADA, Ipputa, TANIZAWA, Yasuhiro, ENDO, Akihito, TOHNO, Masanori, ARITA, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMFH Press 2017
Materias:
Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633531/
https://www.ncbi.nlm.nih.gov/pubmed/29038772
http://dx.doi.org/10.12938/bmfh.17-006
Descripción
Sumario:Being an autochthonous species in humans, Lactobacillus gasseri is widely used as a probiotic for fermented products. We thoroughly compared the gene contents of 75 L. gasseri genomes and identified two intraspecific groups by the average nucleotide identity (ANI) threshold of 94%. Group I, with 48 strains, possessed 53 group-specific genes including the gassericin T cluster (9 genes) and N-acyl homoserine lactone lactonase. Group II, with 27 strains, including the type strain ATCC 33323, possessed group-specific genes with plasmid- or phage-related annotations. The genomic differences provide evidences for demarcating a new probiotic group within L. gasseri.

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