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Metabolomic and transcriptomic profiling of hepatocellular carcinomas in Hras12V transgenic mice

Activation of the Ras/MAPK pathway is prevalently involved in the occurrence and development of hepatocellular carcinoma (HCC). However, its effects on the deregulated cellular metabolic processes involved in HCC in vivo remain unknown. In this study, a mouse model of HCC induced by hepatocyte‐speci...

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Detalles Bibliográficos
Autores principales: Fan, Tingting, Rong, Zhuona, Dong, Jianyi, Li, Juan, Wang, Kangwei, Wang, Xinxin, Li, Huiling, Chen, Jun, Wang, Fujin, Wang, Jingyu, Wang, Aiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633588/
https://www.ncbi.nlm.nih.gov/pubmed/28941178
http://dx.doi.org/10.1002/cam4.1177