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Metabolomic and transcriptomic profiling of hepatocellular carcinomas in Hras12V transgenic mice
Activation of the Ras/MAPK pathway is prevalently involved in the occurrence and development of hepatocellular carcinoma (HCC). However, its effects on the deregulated cellular metabolic processes involved in HCC in vivo remain unknown. In this study, a mouse model of HCC induced by hepatocyte‐speci...
Autores principales: | Fan, Tingting, Rong, Zhuona, Dong, Jianyi, Li, Juan, Wang, Kangwei, Wang, Xinxin, Li, Huiling, Chen, Jun, Wang, Fujin, Wang, Jingyu, Wang, Aiguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633588/ https://www.ncbi.nlm.nih.gov/pubmed/28941178 http://dx.doi.org/10.1002/cam4.1177 |
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