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Mapping of the binding sites of human histamine N-methyltransferase (HNMT) monoclonal antibodies

OBJECTIVE: Recently, we characterized mouse monoclonal antibodies that allow the specific and sensitive detection of human histamine N-methyltransferase (HNMT). To understand differences in binding characteristics and recognition of enzyme variants we mapped the antibody binding sites. METHODS: Frag...

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Detalles Bibliográficos
Autores principales: Schwelberger, Hubert G., Feurle, Johannes, Houen, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633628/
https://www.ncbi.nlm.nih.gov/pubmed/28791419
http://dx.doi.org/10.1007/s00011-017-1086-7