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Progress in development of bioderived materials for dermal wound healing

Treatment of acute and chronic wounds is one of the primary challenges faced by doctors. Bioderived materials have significant potential clinical value in tissue injury treatment and defect reconstruction. Various strategies, including drug loading, addition of metallic element(s), cross-linking and...

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Detalles Bibliográficos
Autores principales: Da, Lin-Cui, Huang, Yi-Zhou, Xie, Hui-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633688/
https://www.ncbi.nlm.nih.gov/pubmed/29026647
http://dx.doi.org/10.1093/rb/rbx025
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author Da, Lin-Cui
Huang, Yi-Zhou
Xie, Hui-Qi
author_facet Da, Lin-Cui
Huang, Yi-Zhou
Xie, Hui-Qi
author_sort Da, Lin-Cui
collection PubMed
description Treatment of acute and chronic wounds is one of the primary challenges faced by doctors. Bioderived materials have significant potential clinical value in tissue injury treatment and defect reconstruction. Various strategies, including drug loading, addition of metallic element(s), cross-linking and combining two or more distinct types of materials with complementary features, have been used to synthesize more suitable materials for wound healing. In this review, we describe the recent developments made in the processing of bioderived materials employed for cutaneous wound healing, including newly developed materials such as keratin and soy protein. The focus was on the key properties of the bioderived materials that have shown great promise in improving wound healing, restoration and reconstruction. With their good biocompatibility, nontoxic catabolites, microinflammation characteristics, as well as their ability to induce tissue regeneration and reparation, the bioderived materials have great potential for skin tissue repair.
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spelling pubmed-56336882017-10-12 Progress in development of bioderived materials for dermal wound healing Da, Lin-Cui Huang, Yi-Zhou Xie, Hui-Qi Regen Biomater Reviews Treatment of acute and chronic wounds is one of the primary challenges faced by doctors. Bioderived materials have significant potential clinical value in tissue injury treatment and defect reconstruction. Various strategies, including drug loading, addition of metallic element(s), cross-linking and combining two or more distinct types of materials with complementary features, have been used to synthesize more suitable materials for wound healing. In this review, we describe the recent developments made in the processing of bioderived materials employed for cutaneous wound healing, including newly developed materials such as keratin and soy protein. The focus was on the key properties of the bioderived materials that have shown great promise in improving wound healing, restoration and reconstruction. With their good biocompatibility, nontoxic catabolites, microinflammation characteristics, as well as their ability to induce tissue regeneration and reparation, the bioderived materials have great potential for skin tissue repair. Oxford University Press 2017-10 2017-10-09 /pmc/articles/PMC5633688/ /pubmed/29026647 http://dx.doi.org/10.1093/rb/rbx025 Text en © The Author(s) 2017. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Da, Lin-Cui
Huang, Yi-Zhou
Xie, Hui-Qi
Progress in development of bioderived materials for dermal wound healing
title Progress in development of bioderived materials for dermal wound healing
title_full Progress in development of bioderived materials for dermal wound healing
title_fullStr Progress in development of bioderived materials for dermal wound healing
title_full_unstemmed Progress in development of bioderived materials for dermal wound healing
title_short Progress in development of bioderived materials for dermal wound healing
title_sort progress in development of bioderived materials for dermal wound healing
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633688/
https://www.ncbi.nlm.nih.gov/pubmed/29026647
http://dx.doi.org/10.1093/rb/rbx025
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