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Locking system strengthened by biomimetic mineralized collagen putty for the treatment of osteoporotic proximal humeral fractures

The current study is to observe the effect of the locking system strengthened by biomimetic mineralized collagen putty for the treatment of senile proximal humeral osteoporotic fractures. From January 2012 to December 2015, 80 cases of senile patients with osteoporotic proximal humeral fractures wer...

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Autores principales: Peng, Cheng, Wang, Hai-Peng, Yan, Jia-Hua, Song, Tian-Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633693/
https://www.ncbi.nlm.nih.gov/pubmed/29026642
http://dx.doi.org/10.1093/rb/rbx016
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author Peng, Cheng
Wang, Hai-Peng
Yan, Jia-Hua
Song, Tian-Xi
author_facet Peng, Cheng
Wang, Hai-Peng
Yan, Jia-Hua
Song, Tian-Xi
author_sort Peng, Cheng
collection PubMed
description The current study is to observe the effect of the locking system strengthened by biomimetic mineralized collagen putty for the treatment of senile proximal humeral osteoporotic fractures. From January 2012 to December 2015, 80 cases of senile patients with osteoporotic proximal humeral fractures were randomly divided into an observation group and a control group, each group with a total of 40 cases. The control group was simply treated with locking plate. The observation group was treated with locking plate in combination with biomimetic mineralized collagen putty. The therapeutic effect thereby was observed. The excellent and satisfactory rate was 90% in observation group and was 72.5% in control group. The difference between the two groups was statistically significant (χ(2) = 5.3312, P < 0.05). The fracture healing time was 11.82 ± 3.62 weeks in observation group and 19.78 ± 5.46 weeks in control group. The shoulder joint function score was 89.63 ± 8.12 in observation group and 76.92 ± 8.18 in control group. There was significant difference between the two groups (t = 7.1272; 12.7834, P < 0.05). The complication rate was 10% in the observation group and 32.5% in the control group (χ(2) = 7.3786, P < 0.05). Locking system strengthened by biomimetic mineralized collagen putty has advantages such as accelerating healing of senile proximal humeral fracture, improving the therapeutic effect, reducing the complications. As one of the optimal internal fixation method, it provides a new option for better treatment of senile osteoporotic fracture.
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spelling pubmed-56336932017-10-12 Locking system strengthened by biomimetic mineralized collagen putty for the treatment of osteoporotic proximal humeral fractures Peng, Cheng Wang, Hai-Peng Yan, Jia-Hua Song, Tian-Xi Regen Biomater Research Articles The current study is to observe the effect of the locking system strengthened by biomimetic mineralized collagen putty for the treatment of senile proximal humeral osteoporotic fractures. From January 2012 to December 2015, 80 cases of senile patients with osteoporotic proximal humeral fractures were randomly divided into an observation group and a control group, each group with a total of 40 cases. The control group was simply treated with locking plate. The observation group was treated with locking plate in combination with biomimetic mineralized collagen putty. The therapeutic effect thereby was observed. The excellent and satisfactory rate was 90% in observation group and was 72.5% in control group. The difference between the two groups was statistically significant (χ(2) = 5.3312, P < 0.05). The fracture healing time was 11.82 ± 3.62 weeks in observation group and 19.78 ± 5.46 weeks in control group. The shoulder joint function score was 89.63 ± 8.12 in observation group and 76.92 ± 8.18 in control group. There was significant difference between the two groups (t = 7.1272; 12.7834, P < 0.05). The complication rate was 10% in the observation group and 32.5% in the control group (χ(2) = 7.3786, P < 0.05). Locking system strengthened by biomimetic mineralized collagen putty has advantages such as accelerating healing of senile proximal humeral fracture, improving the therapeutic effect, reducing the complications. As one of the optimal internal fixation method, it provides a new option for better treatment of senile osteoporotic fracture. Oxford University Press 2017-10 2017-07-21 /pmc/articles/PMC5633693/ /pubmed/29026642 http://dx.doi.org/10.1093/rb/rbx016 Text en © The Author(s) 2017. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Peng, Cheng
Wang, Hai-Peng
Yan, Jia-Hua
Song, Tian-Xi
Locking system strengthened by biomimetic mineralized collagen putty for the treatment of osteoporotic proximal humeral fractures
title Locking system strengthened by biomimetic mineralized collagen putty for the treatment of osteoporotic proximal humeral fractures
title_full Locking system strengthened by biomimetic mineralized collagen putty for the treatment of osteoporotic proximal humeral fractures
title_fullStr Locking system strengthened by biomimetic mineralized collagen putty for the treatment of osteoporotic proximal humeral fractures
title_full_unstemmed Locking system strengthened by biomimetic mineralized collagen putty for the treatment of osteoporotic proximal humeral fractures
title_short Locking system strengthened by biomimetic mineralized collagen putty for the treatment of osteoporotic proximal humeral fractures
title_sort locking system strengthened by biomimetic mineralized collagen putty for the treatment of osteoporotic proximal humeral fractures
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633693/
https://www.ncbi.nlm.nih.gov/pubmed/29026642
http://dx.doi.org/10.1093/rb/rbx016
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