Cargando…

System Pharmacology-Based Dissection of the Synergistic Mechanism of Huangqi and Huanglian for Diabetes Mellitus

The rapidly increasing diabetes mellitus (DM) is becoming a major global public health issue. Traditional Chinese medicine (TCM) has a long history of the treatment of DM with good efficacy. Huangqi and Huanglian are one of the most frequently prescribed herbs for DM, and the combination of them occ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yue, Shi-Jun, Liu, Juan, Feng, Wu-Wen, Zhang, Fei-Long, Chen, Jian-Xin, Xin, Lan-Ting, Peng, Cheng, Guan, Hua-Shi, Wang, Chang-Yun, Yan, Dan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633780/ https://www.ncbi.nlm.nih.gov/pubmed/29051733 http://dx.doi.org/10.3389/fphar.2017.00694

Ejemplares similares

Network Pharmacology Analysis of Huangqi Jianzhong Tang Targets in Gastric Cancer
por: Li, Long, et al.
Publicado: (2022)

A Novel Strategy for Decoding and Validating the Combination Principles of Huanglian Jiedu Decoction From Multi-Scale Perspective
por: Wang, Ke-Xin, et al.
Publicado: (2020)

Integrated network pharmacology and serum metabolomics approach deciphers the anti-colon cancer mechanisms of Huangqi Guizhi Wuwu Decoction
por: Pan, Boyu, et al.
Publicado: (2022)

Mechanism of Huangqi Sanxian Decoction Inhibiting Osteoclast Differentiation Based on Network Pharmacology
por: Shi, Jian-Xin, et al.
Publicado: (2022)

Huangqi Decoction Alleviates Alpha-Naphthylisothiocyanate Induced Intrahepatic Cholestasis by Reversing Disordered Bile Acid and Glutathione Homeostasis in Mice
por: Wu, Jia-Sheng, et al.
Publicado: (2017)

Pharmacological and molecular analysis of the effects of Huangqi Jianzhong decoction on proliferation and apoptosis in GES-1 cells infected with H. pylori
por: Hu, Jingnan, et al.
Publicado: (2022)

Huangqi Guizhi Wuwu Decoction Improves Arthritis and Pathological Damage of Heart and Lung in TNF-Tg Mice
por: Wang, Yi, et al.
Publicado: (2022)

Huanglian Jiedu Decoction in the Treatment of the Traditional Chinese Medicine Syndrome “Shanghuo”–An Intervention Study
por: Luo, Keke, et al.
Publicado: (2021)

The Anti-Inflammatory and Anti-Pruritus Mechanisms of Huanglian Jiedu Decoction in the Treatment of Atopic Dermatitis
por: Xu, Yubin, et al.
Publicado: (2021)

A network pharmacology approach for investigating the multi-target mechanisms of Huangqi in the treatment of colorectal cancer
por: Chu, Xiao-Dong, et al.
Publicado: (2021)

Molecular Mechanism of the Effect of Huanglian Jiedu Decoction on Type 2 Diabetes Mellitus Based on Network Pharmacology and Molecular Docking
por: Yin, Bei, et al.
Publicado: (2020)

Huangqi-Danshen decoction protects against cisplatin-induced acute kidney injury in mice
por: Liu, Xinhui, et al.
Publicado: (2023)

Ancient Chinese Medicine Herbal Formula Huanglian Jiedu Decoction as a Neoadjuvant Treatment of Chemotherapy by Improving Diarrhea and Tumor Response
por: Chan, Yau-Tuen, et al.
Publicado: (2020)

New strategies for identifying and masking the bitter taste in traditional herbal medicines: The example of Huanglian Jiedu Decoction
por: Ke, Xiumei, et al.
Publicado: (2022)

Screening of the active Ingredients in Huanglian Jiedu decoction through amide bond-Immobilized magnetic nanoparticle-assisted cell membrane chromatography
por: Liao, Fengyun, et al.
Publicado: (2022)

Effects and Components of Herb Pair Huanglian-Banxia on Diabetic Gastroparesis by Network Pharmacology
por: Liang, Guoqiang, et al.
Publicado: (2021)

Study on the Molecular Basis of Huanglian Jiedu Decoction Against Atopic Dermatitis Integrating Chemistry, Biochemistry, and Metabolomics Strategies
por: Chen, Jing, et al.
Publicado: (2021)

The interaction of MD-2 with small molecules in huanglian jiedu decoction play a critical role in the treatment of sepsis
por: Chen, Guirong, et al.
Publicado: (2022)

Huangqi Guizhi Wuwu decoction in peripheral neurotoxicity treatment using network pharmacology and molecular docking
por: Chen, Tingting, et al.
Publicado: (2022)

Network Pharmacology-Based Study of the Underlying Mechanisms of Huangqi Sijunzi Decoction for Alzheimer's Disease
por: Zhang, Wei, et al.
Publicado: (2021)

Network pharmacology-based screening of the active ingredients and mechanisms of Huangqi against aging
por: Lan, Siyu, et al.
Publicado: (2021)

Effects of Huangqi Liuyi Decoction in the Treatment of Diabetic Nephropathy and Tissue Distribution Difference of its Six Active Constituents Between Normal and Diabetic Nephropathy Mouse Models
por: Wang, Qun, et al.
Publicado: (2022)

System Pharmacology-Based Strategy to Decode the Synergistic Mechanism of Zhi-zhu Wan for Functional Dyspepsia
por: Wang, Chun, et al.
Publicado: (2018)

Metabolomics Analysis Reveals the Protection Mechanism of Huangqi–Danshen Decoction on Adenine-Induced Chronic Kidney Disease in Rats
por: Liu, Xinhui, et al.
Publicado: (2019)

Huangqi Shengmai Yin Ameliorates Myocardial Fibrosis by Activating Sirtuin3 and Inhibiting TGF-β/Smad Pathway
por: Pan, Jianheng, et al.
Publicado: (2021)

Honeysuckle (Lonicera japonica) and Huangqi (Astragalus membranaceus) Suppress SARS-CoV-2 Entry and COVID-19 Related Cytokine Storm in Vitro
por: Yeh, Yuan-Chieh, et al.
Publicado: (2022)

Decoding the Mechanism of Huanglian Jiedu Decoction in Treating Pneumonia Based on Network Pharmacology and Molecular Docking
por: Li, Xianhai, et al.
Publicado: (2021)

Modified Huangqi Chifeng Decoction Attenuates Proteinuria by Reducing Podocyte Injury in a Rat Model of Immunoglobulin a Nephropathy
por: Chang, Meiying, et al.
Publicado: (2021)

Study on the Mechanism of Huanglian Jiedu Decoction in Treating Dyslipidemia Based on Network Pharmacology
por: Gong, Zhaohui, et al.
Publicado: (2022)

Exploring the Active Ingredients and Mechanism of Action of Huanglian Huazhuo Capsule for the Treatment of Obese Type-2 Diabetes Mellitus Based on Using Network Pharmacology and Molecular Docking
por: Wang, Na, et al.
Publicado: (2022)

Investigation of the pharmacological effect and mechanism of mountain-cultivated ginseng and garden ginseng in cardiovascular diseases based on network pharmacology and zebrafish experiments
por: Yu, Ting, et al.
Publicado: (2022)

Investigation of the Underlying Mechanism of Huangqi-Dangshen for Myasthenia Gravis Treatment via Molecular Docking and Network Pharmacology
por: Liu, Miao, et al.
Publicado: (2023)

Involvement of Huanglian Jiedu Decoction on Microglia with Abnormal Sphingolipid Metabolism in Alzheimer’s Disease
por: Qi, Yi-Yu, et al.
Publicado: (2022)

Exploring the Regulatory Mechanism of Modified Huanglian Maidong Decoction on Type 2 Diabetes Mellitus Biological Network Based on Systematic Pharmacology
por: He, Qi, et al.
Publicado: (2021)

A network pharmacology study of mechanism and efficacy of Jiawei Huanglian-Wendan decoction in polycystic ovary syndrome with insulin resistance
por: Shi, Na, et al.
Publicado: (2022)

Pharmacokinetic incompatibility of the Huanglian-Gancao herb pair
por: Zhang, Ji-Quan, et al.
Publicado: (2020)

Insights into the molecular mechanisms of Huangqi decoction on liver fibrosis via computational systems pharmacology approaches
por: Wang, Biting, et al.
Publicado: (2021)

Exploring Molecular Mechanism of Huangqi in Treating Heart Failure Using Network Pharmacology
por: Tao, Yan-gu, et al.
Publicado: (2020)

A System Pharmacology Model for Decoding the Synergistic Mechanisms of Compound Kushen Injection in Treating Breast Cancer
por: Li, Yi, et al.
Publicado: (2021)

Deciphering the Pharmacological Mechanisms of the Huayu-Qiangshen-Tongbi Formula Through Integrating Network Pharmacology and In Vitro Pharmacological Investigation
por: Wang, Zihao, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_fadcrfgnmka0iukp430qkppmnc