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Anti-tumor Activity of miniPEG-γ-Modified PNAs to Inhibit MicroRNA-210 for Cancer Therapy

MicroRNAs (miRs) are frequently overexpressed in human cancers. In particular, miR-210 is induced in hypoxic cells and acts to orchestrate the adaptation of tumor cells to hypoxia. Silencing oncogenic miRs such as miR-210 may therefore offer a promising approach to anticancer therapy. We have develo...

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Detalles Bibliográficos
Autores principales:	Gupta, Anisha, Quijano, Elias, Liu, Yanfeng, Bahal, Raman, Scanlon, Susan E., Song, Eric, Hsieh, Wei-Che, Braddock, Demetrios E., Ly, Danith H., Saltzman, W. Mark, Glazer, Peter M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633812/ https://www.ncbi.nlm.nih.gov/pubmed/29246289 http://dx.doi.org/10.1016/j.omtn.2017.09.001

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